Markus Zweckstetter Selected Research

Frontotemporal Dementia (Semantic Dementia)

1/2021	Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
7/2015	The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.
3/2007	Structural and microtubule binding properties of tau mutants of frontotemporal dementias.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Markus Zweckstetter Research Topics

Disease

56	Parkinson Disease (Parkinson's Disease) 01/2023 - 05/2004
40	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 07/2005
38	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 03/2005
24	Synucleinopathies 01/2023 - 05/2004
8	Tauopathies 01/2023 - 04/2013
7	Dementia (Dementias) 01/2023 - 09/2007
6	Multiple System Atrophy 01/2023 - 06/2013
5	Disease Progression 01/2022 - 06/2013
4	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2016 - 10/2006
3	Infections 01/2022 - 04/2004
3	Frontotemporal Dementia (Semantic Dementia) 01/2021 - 03/2007
3	Pathologic Processes 11/2014 - 12/2005
2	Cognitive Dysfunction 10/2023 - 12/2019
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 01/2021
2	Neoplasms (Cancer) 07/2019 - 09/2007
2	Parkinsonian Disorders (Parkinsonism) 01/2019 - 09/2005
2	Amyloid Plaque 06/2017 - 02/2009
2	Autoimmune Diseases (Autoimmune Disease) 01/2012 - 10/2009
1	Congenital central hypoventilation syndrome 03/2024
1	Hypoventilation 03/2024
1	Pathological Protein Aggregation 10/2023
1	Sarcoma (Soft Tissue Sarcoma) 10/2023
1	Gliosis 01/2022
1	Neuroinflammatory Diseases 03/2021
1	Corticobasal Degeneration 01/2021
1	Lewy Body Disease (Lewy Body Dementia) 01/2020
1	Neurodevelopmental Disorders 01/2019
1	Transthyretin-Related Hereditary Amyloidosis 12/2016
1	Encephalitis (Encephalitis, Rasmussen) 07/2015
1	Melanoma (Melanoma, Malignant) 01/2014
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 02/2013
1	Amyloidosis 07/2010

Drug/Important Bio-Agent (IBA)

49	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2005
35	SynucleinsIBA 10/2023 - 09/2007
31	alpha-SynucleinIBA 01/2023 - 05/2004
18	Amyloid (Amyloid Fibrils)IBA 10/2023 - 09/2007
17	tau Proteins (tau Protein)IBA 10/2023 - 07/2005
10	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2023 - 03/2007
8	Intrinsically Disordered ProteinsIBA 10/2023 - 12/2005
8	Peptides (Polypeptides)IBA 04/2016 - 06/2011
5	Protein Isoforms (Isoforms)IBA 01/2023 - 10/2006
5	SolutionsIBA 11/2021 - 12/2014
5	CopperIBA 09/2017 - 03/2005
5	Prion ProteinsIBA 01/2016 - 10/2006
4	Inosine Diphosphate (IDP)IBA 01/2022 - 06/2010
4	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2022 - 10/2018
4	LigandsIBA 01/2022 - 07/2015
4	Proline (L-Proline)FDA Link 01/2022 - 12/2020
4	MetalsIBA 05/2014 - 08/2006
2	fasudil (AT 877)IBA 01/2022 - 04/2016
2	DipeptidesIBA 01/2022 - 01/2021
2	Arginine (L-Arginine)FDA Link 01/2022 - 01/2021
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2019
2	Molecular Chaperones (Chaperone, Molecular)IBA 01/2021 - 01/2017
2	3- (1,3- benzodioxol- 5- yl)- 5- (3- bromophenyl)- 1H- pyrazoleIBA 01/2018 - 06/2013
2	Amyloidogenic ProteinsIBA 06/2017 - 09/2011
2	SirtuinsIBA 01/2017 - 01/2017
2	Prealbumin (Transthyretin)IBA 01/2017 - 12/2016
2	Protein AggregatesIBA 04/2016 - 01/2016
2	Serine (L-Serine)FDA Link 01/2016 - 06/2008
2	Macrophage Migration-Inhibitory FactorsIBA 01/2012 - 10/2009
2	Anti-Bacterial Agents (Antibiotics)IBA 09/2004 - 04/2004
1	polyalanineIBA 03/2024
1	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2023
1	Dextrans (Dextran)FDA Link 01/2023
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2022
1	Transcription Factors (Transcription Factor)IBA 11/2022
1	Phenylalanine (L-Phenylalanine)FDA Link 11/2022
1	Cyclin-Dependent Kinase 2IBA 10/2022
1	Nucleocapsid ProteinsIBA 01/2022
1	pontamine sky blueIBA 01/2022
1	IronIBA 11/2021
1	Biomarkers (Surrogate Marker)IBA 03/2021
1	Doxycycline (Periostat)FDA LinkGeneric 01/2021
1	PolymersIBA 01/2021
1	Alanine (L-Alanine)FDA Link 01/2021
1	Mutant Proteins (Protein, Mutant)IBA 01/2021
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020
1	BSC4090IBA 12/2019
1	1,4- bis(4'- hydroxystyryl)- 2- methoxybenzeneIBA 12/2019
1	PhosphoproteinsIBA 01/2019
1	Lysine (L-Lysine)FDA Link 01/2019
1	Dopamine (Intropin)FDA LinkGeneric 01/2019
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	Sirtuin 2IBA 01/2017
1	PK 11195 (PK11195)IBA 08/2015
1	Selegiline (E250)FDA LinkGeneric 12/2014
1	MART-1 AntigenIBA 01/2014
1	AntigensIBA 01/2014
1	Toll-Like Receptor AgonistsIBA 01/2014
1	peptide AIBA 01/2014
1	PrionsIBA 06/2013
1	EpitopesIBA 06/2013
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 04/2013
1	Amyloid beta-PeptidesIBA 01/2011
1	ElementsIBA 12/2009
1	CytokinesIBA 10/2009
1	gamma-Synuclein (Persyn)IBA 09/2007

Therapy/Procedure

5	Therapeutics 03/2024 - 06/2013